Denny Duquette tops my list of fictional deaths I will never get over. This episode had me bawling. My heart hurt so bad when Denny died after proposing to Izzy. He was such a lovable character, and he was so handsome! I rooted for the two of them to as a couple. You can only imagine my heartache. P.S Kudos to you, Katherine Heigl on the amazing performance. The list of saddest Grey's Anatomy episodes is going to get just more heartbreaking.

This was such a nerve wracking episode to watch. I mean, I knew Meredith wouldn't actually die. After all, the show is pretty much based around her. But, nonetheless, it was still a very sad moment when Meredith flatlined. I felt the pain everyone was feeling and I felt the relief they all had when her heart started beating again.

O'Malley. Where do I even begin? George was so easy to love. He'd gone through so much in the show and you just couldn't help but root for him. I think the show did a great job on his portrayal. Even though I wish George would've lived and continued to work with them all, I'm glad he died by doing something noble. It's very much "George O'Malley."

This episode had me biting my nails the entire time. From start to finish, my heart was racing. Not only did Derek Shepherd get shot in this episode, but so did Alex. I don't know what I'd have done if either of them had died in this episode! Thankfully, they're both still with us.

Teddy took a long time to open up and love Henry, but when she did, they were perfect together. Everything about this clip makes me emotional. The song in the background, Teddy asking Christina what happened, etc. I think the acting was really fantastic in this episode.

Cue the tears. Lexie and Sloan were my favorite couple on Grey's (aside from Meredith and Derek). When Lexie died, I was so crushed. This episode served as the season 8 finale, and like every other finale, it made me cry like a baby. Sloan was so in love with her and his final declaration of love was so touching.

What a way to start off season 9, right? More heartache! In this episode, Mark Sloan died. What made this episode so sad was that Mark awoke from his coma, was doing fantastic, and then crashed and died. As heartbreaking as it was, I was sort of relieved that Mark would be joining his love, Lexie, even though it meant leaving everyone else behind.

There you have it! Turns out the saddest episodes (for me) all involved a character's death/injury. Which episode will you never get over?